Sunday, January 6, 2013

Non-Hodgekins Lymphoma... things related

My mom has Non-Hodgekin's Lymphoma. .. Here are some things related to this...
    and dealing with that and maybe other things along the way..
                                   I'm not sure yet..
         Ref:  Non-Hodgkin_lymphoma   in WiKi.
       lymphoma-non-hodgkin/subtypes Subtypes..




1]  Diagnosed Nov. 2011.. started with another doctor saying that she had
     something like Agglutin Disease (?).. Red Blood Cells looked funny.
     So, they did a procedure that I held her hand throughout.. taking some
    bone merrow out of her back/pelvis area..  (I know it was may more
    painful for her than me.. but.. I hope I never have to go thru that
    as an observer OR a participant...please, Lord!?)

2]  She had a fantastic doctor.. Dr. Patricia Deisler .. for a year..
      I loved that this woman was positive, supportive,  and knowledgable
      in nutrition!  But, she's moved on as of  Nov 2012..

3]   This week, my moms blood count was 'better' than previous.. but
       they added in a "Coomb's Test for Antiglobulin..
       I presume this is a DAT (Direct) test for Auto Immune
     Hemolytic Anemia ..   It shows if her low RBC is due to
     the RBC membraines causing RBC destruction.
     Ref:    Coombs_test  in Wiki. 





Functional status
To determine a patient’s prognosis, the doctor may also test how well a patient is able to function and carry out daily activities by using a functional assessment scale, such as the Eastern Cooperative Oncology Group (ECOG) Performance Status or the Karnofsky Performance Scales (KPS).
ECOG Performance Status. A lower score indicates a better functional status. Typically, the better someone is able to walk and care for himself or herself, the better the prognosis.
0: Fully active, able to carry on all pre-disease performance without restriction
1: Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, such as light house work or office work
2: Ambulatory and capable of all self-care but unable to carry out any work activities. Up and about more than 50% of waking hours
3: Capable of only limited self-care; confined to bed or chair more than 50% of waking hours
4: Completely disabled; cannot carry on any self-care; totally confined to bed or chair
5: Dead
KPS. A higher score indicates a better functional status.
100: Normal, no complaints, no evidence of disease
90: Able to carry on normal activity; minor symptoms of disease
80: Normal activity with effort; some symptoms of disease
70: Cares for self; unable to carry on normal activity or active work
60: Requires occasional assistance but is able to care for needs
50: Requires considerable assistance and frequent medical care
40: Disabled; requires special care and assistance
30: Severely disabled; hospitalization is indicated, but death is not imminent
20: Very sick; hospitalization necessary; active treatment necessary
10: Approaching death; fatal processes progressing rapidly
0: Dead
staging   that's where the above ECOG and KPS came from.
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Bone marrow aspiration and biopsy: These procedures are often done after lymphoma has been diagnosed to help determine if it has reached the bone marrow. The two tests are often done at the same time. The samples are usually taken from the back of the pelvic (hip) bone, although in some cases they may be taken from the sternum (breast bone) or other bones.
In bone marrow aspiration, you lie on a table (either on your side or on your belly). After cleaning the skin over the hip, the doctor numbs the area and the surface of the bone with local anesthetic, which may cause a brief stinging or burning sensation. A thin, hollow needle is then inserted into the bone and a syringe is used to suck out a small amount of liquid bone marrow (about 1 teaspoon). Even with the anesthetic, most patients still have some brief pain when the marrow is removed.
A bone marrow biopsy is usually done just after the aspiration. A small piece of bone and marrow is removed with a slightly larger needle that is twisted as it is pushed down into the bone. The biopsy may also cause some brief pain. Once the biopsy is done, pressure will be applied to the site to help stop any bleeding.
 Bone Marrow Aspiration     (where the above info came)
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